SciTech

That Pill Could Kill You

port1080.

Posted to SciTech on Fri Feb 09, 2007 at 02:55:01 AM EST (promoted by 1fastdog). RSS.

Women today face a plethora of different birth control options. Aside from the venerable condom, oral contraceptive pills are probably the number one choice due to their exceptionally low failure rate and ease of use.

Today's pill is not your mother's pill, however. There are a multitude of pills on the market, some of which work in significantly different ways. Health interest group Public Citizen recently argued in a filing before the FDA that not all of these changes have been for the better. The group claims that many third generation pills which feature desogestrel can cause an increased risk of life threatening blod clots while giving no advantage to the consumer, and thus should be pulled from the market. The petition cited Johnson & Johnson's Ortho-Cept, Watson Pharmaceuticals Inc.'s Reclipsen, Barr Pharmaceuticals' Mircette, Velivet, Kariva and Apri-28, and Organon's Desogen, as well as generics of similar formulation.

It has long been known that taking the pill can cause blood clots (the FDA has required that the risk be disclosed in pill packaging since 1995). The potential for clots rises significantly for smokers and women with certain health conditions. The so-called third generation pills (those containing desogestrel) are known to increase this risk even more (in comparison to earlier formulations of the pill). Considering that the wide acceptance of the pill, and the trend to prescribe it not just for birth control, but also to relieve menstrual cramps and even to help clear up acne, is the government doing enough to make women aware of the potential medical complications that they may face from its use?

Tags: written by Port1080, edited by 1fastdog, birth control, blood clots, the pill, drugs (all tags)

This story: 16 comments (5 from subqueue)
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Re: That Pill Could Kill You

port1080.

Fri Feb 09, 2007 at 10:28:13 AM EST

none

I'm very divided on this issue...while I think the pill has in general been an exceptionally Good Thing(tm), I also feel that sometimes it's just handed out like candy to young women (particularly women in college), with little explanation of potential side effects. If you just do a simple web search you'll turn up hundreds of first person accounts of women who have had all sorts of minor-to-major complications from the pill. I've had friends and ex-girlfriends who have had all sorts of problems with it, and about an equal number who have taken it with little to no side effects. Some of the side effects (like mood swings or lost sex drive) can easily be written off to other factors, so if you're not aware that the pill can cause them you might not even make the connection.

People also tend to assume that all pills are essentially the same, but in fact they all have somewhat different side effects and somewhat different failure rates. Bringing up something thefadd mentioned in the sub-q, the newer low dose pills have a failure rate that's about double that of the older, high dose pills. It's still a very low failure rate, but a friend of mine who switched from hi dose to low dose pills due to her blood pressure was not made fully aware of the difference by her doctor (she only found out by comparing the fine print on the fact sheets that came with her old pills to the one that came with her new pills). The combination of the desire of pharmaceutical marketing departments to downplay side-effects, and our American cultural hesitation to have honest discussions about anything that relates to sex, has led to a culture where a large portion of adult women are taking a drug that they don't really know all that much about.

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Re: That Pill Could Kill You

cloudofdust.

Fri Feb 09, 2007 at 11:00:05 AM EST

none

I'm very divided on this issue...while I think the pill has in general been an exceptionally Good Thing(tm), I also feel that sometimes it's just handed out like candy to young women (particularly women in college), with little explanation of potential side effects.

Is that true? Are women really that ignorant of the side effects? When I was in college an acquaintance died from just such a blood clot. All my female friends seemed well aware of the risks and that those risks rose significantly for smokers. And that was over 15 years ago.

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Re: That Pill Could Kill You

port1080.

Fri Feb 09, 2007 at 12:05:55 PM EST

none

Is that true? Are women really that ignorant of the side effects?

Well, I think it's one of those things that hinges on how you understand the risk. For example, I knew the health center staff at my undergrad university fairly well. The head of the health center (a nurse practitioner - they had doctors on call, but it was a small school so they were only on as part-time staff) was the adviser to an AIDS awareness group that I was in, and she made it clear to us that it was her opinion that pretty much every girl in the school should be on the pill. She dealt with so many tearful "morning after" stories, and had to set up so many behind-the-parent's (or boyfriend's) back abortions that she felt the small risk of harm more than offset the benefits. I'm sure that when she talked to girls about going on the pill, she made them fully aware of the side effects - but also highly encouraged them to go on it, and emphasized that the risk of complications developing is actually very low. So yes, all the girls that went through her "knew" the risks, but they also "knew" that the pill was very safe and effective. On the flip side, an acquaintance of mine went through her family gynecologist to go on the pill as was put on the old school, high dose pill. When she went back for her six-month checkup, her blood pressure was higher than it should have been, and the gynecologist gave her a scare story lecture and took her off the pill, but didn't make any effort to switch her to a low dose pill or alternative form of birth control. About two years later she went on one of the low dose pills (through another gynecologist), and hasn't had any problems with her blood pressure since.

These varying experiences suggest to me that knowledge about the pill's effects probably varies widely depending on the circles you move in, the culture of the place that you got your pill prescription from (i.e. family planning clinics and college health centers will probably push the pill a bit harder than a family doctor might). Since the pill still has some stigma attached to it, I don't think women are quite as comfortable talking about it (both to their medical provider, and amongst each other), which leads to a lot of misinformation. That cuts both ways, of course - in general discussion I've found that a lot of people think the pill is less effective than it actually is (it's about 98%-99% effective when taken absolutely on schedule, and about 92%-95% effective in "real life" situations - but I've had a lot of people swear to me that it was in the 80% range). Ideally, this is the sort of thing that would be covered honestly in a high school health class, but in the current climate I suppose that's a bit much to expect. A truly honest assessment gets attacked from both the far left and the far right (the left because some will claim that even admitting there are risks somehow makes you an oppressor, and the far right's issues with the pill are pretty well known). It's a tough issue no matter how you look at it.

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Re: That Pill Could Kill You

nmiguy.

Fri Feb 09, 2007 at 11:42:46 AM EST

none

with little explanation of potential side effects

Really?  I thought when you get birth control pills they come with a sheet warning of teh side effects.  That every time you get a supply of kids you can get this warning.  

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Re: That Pill Could Kill You

port1080.

Fri Feb 09, 2007 at 12:09:13 PM EST

none

I thought when you get birth control pills they come with a sheet warning of teh side effects.

They do, of course, but how many people actually read that sheet in detail? Also, as I mentioned in my reply to cloudofdust, the attitude of the person who initially prescribes the pill to you can have a large impact on how you assess that risk (i.e. whether you blow it off, or take it seriously).

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Re: That Pill Could Kill You

gerrymander.

Fri Feb 09, 2007 at 10:50:54 AM EST

none

Desogestrel -- isn't that in the same synthetic molecule family as the now-OTC "Plan B" medicine levonorgestrel? The same "Plan B" medication some women's rights activists want to make freely available to girls as young as fourteen? Why, yes it is.

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Re: That Pill Could Kill You

Lou.

Fri Feb 09, 2007 at 11:34:47 AM EST

none

Having some difficulty with the concept of plan B?

It's the end of the world as we know it, and I feel fine

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Hell, why not bring back the Dalkon Shield, too?

gerrymander.

Fri Feb 09, 2007 at 12:10:52 PM EST

none

Having some difficulty with the concept of plan B?

Look, Lou, maybe you don't recall the "no wire hangars" pro-legalized abortion campaign, but I do. The whole point of a legal right to choose was coached as a means to keep women safe. So maybe I'm a bit touchy about pregnancy prevention measures which might have the same net result as back alley hack jobs. Maybe you should be.

(For the record, I'm not against Plan B medication, but I am very much against Plan B being made available over-the-counter.)

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Re: Hell, why not bring back the Dalkon Shield, to

Lou.

Fri Feb 09, 2007 at 12:50:31 PM EST

none

Despite my youthful good looks I do remember the no hangers times.  Are you saying that Plan B is more dangerous than back alley wire hangers?  And as far as saying plan B being dangerous, well hell, parachutes are dangerous...but in the right circumstances, it's far better than the alternative.

And for the record, I'm not sure where I stand on the OTC aspect of this drug...especially for minors*.  I would hope that women would use it ONLY** as a plan b and not as a regular form of birth control.  

*Insert standard argument here...old enough to pursue an adult activity, old enough to pursue an adult remedy.

**This is a faint hope, I know.

It's the end of the world as we know it, and I feel fine

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Re: Hell, why not bring back the Dalkon Shield, to

Thalia.

Fri Feb 09, 2007 at 05:31:13 PM EST

none

Why do people consistently make statements like "people use abortion as a method of birth control"?  Where does that come from?  It annoys me incredibly.  I want a new equivalent meme about people who don't floss twice a day "using root canals as a form of tooth care."  It's not a substitute, no one would choose the expensive & painful route, but people often neglect routine maintenance until they have an emergency situation.

/snark

Thalia

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Re: Hell, why not bring back the Dalkon Shield, to

gerrymander.

Fri Feb 09, 2007 at 07:07:50 PM EST

none

Are you saying that Plan B is more dangerous than back alley wire hangers?

I'm worried that Plan B may pose significant danger when taken without medical guidance, being as it is a pair of megadoses of the same drug family in the suit noted above. I acknowledge that my worry is currently based on speculation -- but not, I think, a foolishly unfounded one.

If, God forfend, I'm right, then for a time Plan B will be more dangerous than a back alley wire hanger, if only for the innocuous appeal of the former. Eventually, some doctor would come to the right conclusion about the circumstances of X dozen women's deaths, and Plan B would be off the menu permanently.

Frankly, I'd rather be wrong in this case.

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Re: Hell, why not bring back the Dalkon Shield, to

housewife2000.

Sat Feb 10, 2007 at 12:24:44 AM EST

none

 I would hope that women would use it ONLY** as a plan b and not as a regular form of birth control.  

The effects that plan b brings on in order to prevent pregnancy make the chances of it being used as a regular birth control very slim. Violent nausia, heavy bleading, severe cramping..all of which last about a week, does not a fun time make.

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Perhaps I misspoke

Lou.

Sat Feb 10, 2007 at 09:44:40 AM EST

none

I didn't mean to imply that using plan b would be a regular form of birth control for most women.  I do know that this method would only be used as one uses a parachute to escape from critically damaged aircraft.  I don't think there are any sport jumpers/plan b users.

It's the end of the world as we know it, and I feel fine

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Re: That Pill Could Kill You

Thalia.

Fri Feb 09, 2007 at 05:33:47 PM EST

none

There is an increase in blood clots over YEARS of use.  If you contrast using Plan B with having a surgical abortion, I think you will find that Plan B's risks are significantly less than the risk of a D&C.

Thalia

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Re: That Pill Could Kill You

3fingerspointback.

Tue Feb 13, 2007 at 03:04:39 AM EST

none

Oh my goodness!  A drug comes from the same molecule family as another drug!  Do you have a point with that factoid, or have you been posting while drinking methyl alcohol?

(is 3fingerspointback)

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Re: That Pill Could Kill You

housewife2000.

Sat Feb 10, 2007 at 12:26:51 AM EST

none

The pill is used to treat so many things right now, and affect so many women differently that, no, most are not aware of the side affects. I have horrible headaches on some, nothing on others, dizziness and lathargy have been experienced as well. Two of my kids were concieved on the pill, one a low dose, one a rediculously high dose... What's really comical about all this, I have never had a prescription for birth control reasons...always for some other health issue that might be affected.

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